Post Doc Position In Transcription Factor Activation Domains University of Copenhagen Department of Biology, Faculty of Science Denmark

 Several Post Doc Positions Available Within REPIN – Rethinking Protein Interactions

 
REPIN, Department of Biology, Faculty of Science, University of Copenhagen, has a number of positions available from August 1, 2019, or soon thereafter. The positions are part of the newly funded Novo Nordisk Foundation Challenge Center REPIN- rethinking protein interactions. REPIN connects research groups in Copenhagen and Zürich to study interactions of Intrinsically Disordered Proteins (IDPs) using a suite of biophysical methods and ranging from the single atom and molecule over ensembles to organisms. 
 
 
Post doc position in transcription factor activation domains 

 
A post doc position (2 year’s with the possibility of extension) will be available to study how protein disorder regulates the function of transcription factor activation domains. Focus will be on their interactions with general transcriptional regulators, higher order complexes and participation in liquid-liquid phase separation processes. The project will elucidate how compaction properties of a disordered chain and coacervation will influence activation mechanisms.  
 
 
Qualifications: 

We are seeking a highly motivated applicant with a PhD degree in chemistry, biophysics or biochemistry or similar fields with documented competences in 
 
  • Protein expression and purification including optimization of protocols 
  • Biophysical studies of IDPs 
  • Biophysical techniques as ITC, stopped-flow, CD, NMR or fluorescence spectroscopy, or small angle X-ray scattering 
  • Cellular and molecular biological techniques  
  • Applied bioinformatics  
  • Publications in peer-reviewed scientific journals 
  • Good English oral and written competence 
 
It will also be advantageous to have experience with one or more of the following: 
  • Molecular dynamics 
  • Liquid-liquid phase separation 
  • Microscopy 
 
For further information about the position, please contact Professors Karen Skriver (kskriver@bio.ku.dk) or Birthe B. Kragelund (bbk@bio.ku.dk), Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/.  
 
 
Post doc position in yeast genetics and biophysics 
 
 
A post doc position (2 years) will be available for the studies of disordered proteins in yeast. The project is aimed at structural and functional characterization of small IDPs by NMR spectroscopy and various cellular assays translating observations from in vitro to in vivo. 
 
 
Qualifications
 
We are seeking a highly motivated applicant with a PhD degree in genetics, biophysics or biochemistry or related fields with documented competence in 
 
  • Molecular biology with yeast and E. coli  
  • Biophysical techniques as ITC, stopped-flow, CD, NMR or fluorescence spectroscopy, or small angle X-ray scattering 
  • Protein chemistry 
  • Good oral and written English competences 
  • Publications in peer-reviewed scientific journals 
 
It will also be advantageous to have experience with one or more of the following: 
 
  • Protein NMR spectroscopy 
  • Analyses of protein interactions 
  • Quantitative MS 
  • In cell NMR spectroscopy
 
For further information about the position, please contact Professors Rasmus Hartmann-Petersen (RHPetersen@bio.ku.dk) or Birthe B. Kragelund (bbk@bio.ku.dk). Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/.  
 
 
The post doc positions are open from 1 August 2019 or as soon as possible thereafter.  
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background. 
 
 
Terms of employment 
 
The positions are covered by the Memorandum on Job Structure for Academic Staff.  
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.  
The starting salary is currently up to DKK 426.625 including annual supplement (+ pension up to DKK 72.952). Negotiation for salary supplement is possible. 
The application, in English, must be submitted electronically by clicking APPLY NOW below.  
 
 
Please include  
  • A 1-page letter explaining the applicant´s background, key competence in relation to the position and reasons for applying 
  • A 1-page curriculum vitae including a list of peer-reviewed publications (may include papers under review) 
  • Master diploma including grades 
  • PhD diploma including any written evaluation if applicable 
  • Contact details for 2 former employers or supervisors 
 
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Interviews will be conducted in May. 
 
 
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
 

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

 

Info

Application deadline: 30-04-2019
Employment start: 01-08-2019
Working hours: Full time
Department/Location: Department of Biology


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