Postdoctoral Researcher in Cell Biology and Laboratory Automation
University of Helsinki, Faculty of Medicine
Finland

The Faculty of Medicine promotes scientific research of a high standard and is responsible for providing research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, as well as for the English-language Master’s Programme in Translational Medicine. In addition to its teaching and research activities, the Faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. In terms of research, the Faculty aims for a place among the best medical faculties in the world, while consolidating and strengthening its status as a top-level institution of medical education.

 

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

 

The Faculty of Medicine is seeking a

 

POSTDOCTORAL RESEARCHER IN CELL BIOLOGY AND LABORATORY AUTOMATION

 

Dr. Simon Pfisterer is setting up a new research group at the Department of Anatomy, Faculty of Medicine, University of Helsinki, and is looking for a highly motivated postdoctoral researcher to join his multi-disciplinary team.

 

Hypercholesterolemia, an elevated blood concentration of low-density lipoprotein (LDL) increases the risk for cardiovascular disease, which is one of the most common causes for death worldwide. Individuals respond differently to LDL lowering medications. Currently, we do not understand the cellular defects underlying increased blood LDL concentration and how different responses to LDL lowering therapies arise in individual patients.

 

It is the goal of the research team to set up state-of-the-art laboratory automation tools to elucidate cellular mechanisms underlying the development of hypercholesterolemia. For this purpose, we will establish a work environment where cell biological research is truly merging with laboratory automation and programming.

 

We are looking for a highly motivated individual with a commitment to excellence to join this dynamic and collaborative research team. Ideal candidates have a strong background in cell and molecular biology and are eager to acquire new skills such as automated image and data analysis. Key requirements are experience in human cell culture methods, molecular cloning (e.g. generation of expression plasmids), and fluorescence microscopy. Experience in Python programming or automated image analysis are a plus. A PhD degree in Life or Biological sciences, or an MD PhD degree, as well as excellent communication skills in spoken and written English, are required.

 

We provide opportunities to develop both transferable and scientific skills, with strong support from your laboratory colleagues, and competitive salary (3100-3600 euros/month).

 

The application, together with the required attachments, must be submitted through the University of Helsinki electronic recruitment system by clicking the Apply for job -link. Internal applicants (i.e. current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

 

The application should include a cover letter describing previous achievements and motivation for the position (1 page), CV, track record of peer-reviewed publications, and names and contact details of two referees.

 

Apply by 01.09.2019

 

The position will be filled once a suitable candidate has been identified. The initial appointment is for one year starting as soon as possible, with the possibility of extension. A six-month trial period will be applied.

 

Further information is available from simon.pfisterer(at)helsinki.fi

 

Recent publications:

1.Pfisterer, S. G. et al. Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage. Nat. Commun. 8, 14858 (2017).
2.Sandhu, J., Pfisterer S.G. et al. Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells. Cell 175, 514-529.e20 (2018).
3.Pfisterer, S. G., Peränen, J. & Ikonen, E. LDL-cholesterol transport to the endoplasmic reticulum: current concepts. Curr. Opin. Lipidol. 27, 282–287 (2016).

 

Due date

01.09.2019 23:59 EEST


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