Research Fellow in Molecular mechanisms of Prim-Pol - dependent pathways involved in DNA repair
University of Sussex, School of Life Sciences / Genome Damage and Stability Centre
United Kingdom

Research Fellow : Molecular mechanisms of Prim-Pol - dependent pathways involved in DNA repair


School/department: School of Life Sciences / Genome Damage and Stability Centre


Hours: full time or part time hours considered up to a maximum of 1.0 FTE. Requests for flexible working options will be considered (subject to business need).


Contract: fixed term for 2 years


Reference: 1991


Salary: starting at £33,199 and rising to £39,609 per annum


Placed on: 5 August 2019


Closing date: 4 September 2019. Applications must be received by midnight of the closing date.


Expected start date: within 1 month of 1st October 2019

 

Job description


The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014.

 

Applicants are invited to apply for a BBSRC-funded postdoctoral position to study novel DNA repair mechanisms. Cells possess a myriad of DNA maintenance pathways required to ensure genome stability. The aim of this project is to study the molecular mechanisms of Primase-Polymerases (Prim-Pols), and their complexes, involved in DNA repair processes in mycobacteria. Specifically, we would like to characterise the components of specific repair complexes and define their molecular mechanisms by reconstituting these pathways in vitro. Applicants must have extensive experience in using biochemical, biophysical and structural techniques to study the molecular interactions and mechanisms of protein complexes involved in DNA / RNA repair, replication, transcription or related cellular processes.

 

The successful applicants will join the Genome Damage and Stability Centre, an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease. We provide a stimulating and supportive research environment and our expertise covers a wide range of experimental systems. Further information about our research can be obtained from our website at http://www.sussex.ac.uk/gdsc/.

 

What we offer:

A highly motivated and dedicated international team.
Innovative projects at the forefront of this research field.
Excellent collaborative research facilities and environment.
Collaborations with many labs in our centre and abroad.
A project where your contribution will make a real impact!


The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Silver Award. Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in Science, Technology, Engineering, Medicine and Mathematics (STEMM) at Sussex. The School of Life Sciences welcomes applications to academic posts from candidates who wish to work part-time or as job-sharers.

 

The University offers various schemes to provide real benefits to parents, these can be found at Family Friendly Policies

 

Potential candidates are strongly encouraged to make informal contact with Prof. Aidan Doherty before applying. E-mail: AJD21@sussex.ac.uk ; Tel: +44 1273 877500.

 

The University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds

 

Download job description and person specification Ref 1991 [PDF 89.70KB]

 

How to apply


Download our academic post application form [DOC 301.50KB] and personal details and equal opportunities form [DOC 162.50KB] and fill in all sections.

 

Applications should be accompanied by a full CV, a statement of research interests and aspirations (not more than 4 pages), and the names of three academic referees.

 

Email your completed application, full CV, a statement of research interests and aspirations, and personal details and equal opportunities form, to lifescirecruitment@sussex.ac.uk

 

You should attach your application form and all documents to the email (don't use a web-based upload/weblink service) and use the format job reference number / job title / your name in the subject line.

 

You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.

 

Download our terms and conditions summary for Research Faculty Terms and Conditions [DOC 36.00KB]


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