Postdoctoral fellowship on protein self-assembly and aggregation for biomaterials University of Copenhagen, Department of Pharmacy Denmark

Postdoctoral fellowship on protein self-assembly and aggregation for biomaterials

 

A three-year postdoctoral fellowship on protein self-assembly and aggregation for biomaterials is available from May 1st, 2019 or soon thereafter at the Department of Pharmacy at the University of Copenhagen (KU) in Denmark.  

 

The fellowship will be part of a 5-year research project titled “Protein Superstructures as Smart Biomaterials (ProSmart)”, financed by a “Villum Young Investigator Grant” to Associate Professor Vito Foderà (team website and research profile at KU). The project will be based at the excellent research environment of the Department of Pharmacy at the University of Copenhagen and in collaboration with the “Center for Biopharmaceuticals and Biobarriers in Drug Delivery” (http://biodelivery.ku.dk/om/), the Department of Chemistry at the University of Copenhagen and the University of Cambridge (UK).  

 

The Department of Pharmacy at the University of Copenhagen is devoted to research and research-based teaching in drug formulation and manufacturing, drug-related analytical and physical chemistry, drug metabolism, chemical toxicology and medicines use. The Department plays a key role in advancing the pharmaceutical sciences in Denmark and internationally. The scientific and teaching objectives of the Department encompass the areas of Pharmaceutical Technology and Engineering; Advanced Drug Analysis; Pharmaceutical Design and Drug Delivery; Biologics; and Clinical and Social Pharmacy. Read more about Department of Pharmacy at http://pharmacy.ku.dk/  

 

Project overview and job description  

Biomaterials are expected to play a major contribution to the manufacturing of pharmaceuticals as well as for applications in tissue engineering, bio-sensing and drug delivery. In connection to these fields, having tunable materials whose properties can be rationally controlled is necessary and still remains a major challenge. The project has as a main objective to develop a platform for the rational design of highly tunable protein-based materials for drug delivery. To reach this goal, optical, UV and IR spectroscopies in combination with small angle X-ray scattering (SAXS) and quantitative modeling will be employed.  

 

The Postdoc´s duties will primarily include research, including obligations with regard to publication/scientific communication, grant writing, proposal writing for experiments at large-scale facilities, PhD and MSc students co-supervisions within the area of protein biophysics and aggregation, and research-based teaching.  

 

The successful applicant will specifically work on the analysis of a variety of protein aggregate structures, with the aim of providing a connection between inter-protein interactions, kinetics of aggregate growth, aggregate structures and physico-chemical properties. He/she will work closely with a biophysicist/biochemist PhD student (focusing on protein aggregation kinetics) and, lately in the project, with a cell biologist Postdoc (mainly focusing on the application of the different protein self-assembled structures as efficient delivery systems of biologically-relevant compounds). All these projects will also benefit of the existing projects currently running in the group (1 Postdoc and 4 PhD students).  

 

Required Qualifications  

In connection with the appointment special importance will be attached to the applicant having the professional and personal qualifications stated below:  

  • Documented scientific qualifications such as a Ph.D. or equivalent in (bio)physics, (bio)chemistry, biology, pharmaceutical sciences, nanotechnology or related areas.  

  • At least two first-author publications in respectable peer-review international journals.  

  • Excellent English speaking, reading and writing skills.  

  • Creativity and ability to be both team-oriented and independent  

  • Capability of working at the interface between different disciplines  

  • Embrace of an international research environment  

Preferred Qualifications  

We are looking for a highly motivated, academic-oriented scientist with the attitude towards quantitative analysis of the experimental data. The ideal candidate should also have a strong background in/hands-on research experience within one or several of the fields mentioned below:  

  • protein science  

  • small-angle X-ray scattering  

  • protein aggregation  

  • structural biology  

  • biophysical characterization of protein samples  

  • microscopy-based techniques  

  • optical and IR spectroscopy  

  • theoretical modeling of aggregation kinetics  

Highly motivated and ambitious candidates are encouraged to apply. Solid experience and an excellent track record gained in the field of protein biophysics and aggregation will be considered a distinct advantage. We encourage all the qualified individuals- regardless of their personal background and status - to apply.  

 

Further information  

For further information, please contact Associate Professor Vito Foderà (vito.fodera@sund.ku.dk, tel. +45 35336131).  

 

Terms of employment  

The terms of employment and payment are according to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. As an equal opportunities employer, the University of Copenhagen encourages all qualified applicants to apply, regardless of gender, age, religion and ethnic origin. The period of employment as post doc will be limited to 3 years.  

 

Application  

Applications should include the following parts:   

  1. application in the form of a cover letter indicating the motivation, interest in and qualifications for the project (max 2 pages).  

  2. curriculum vitae, including the names, e-mails, telephone numbers and addresses of at least 2 referees.  

  3. Max. 1 recommendation letter.  

  4. copies of relevant diplomas (e.g. education, teaching and additional research qualifications)  

  5. a complete list of publications indicating articles relevant to the position, including copies of these articles (max. 5)  

The parts must be clearly labeled with the above-mentioned numbers. Send your application with the above mentioned appendices electronically by clicking the ´Apply online´ below. We only accept electronic applications.  

 

Deadline for application is 24 February 2019 at 11:59 PM CET. Applications received after the deadline, not using the online application form, or not including the required documents will not be considered.  

 

Application procedure  

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk  

Selected candidates will be called for interviews that will be held between the end of March and beginning of April 2019. An answer as to the granting of the fellowship can be expected soon after the interviews.


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