Doctoral Student in Medical Science - Biomaterial Diary id:PAR 2020/834 Employment level:Fixed term Location:Institute of Clinical Sciences Apply by:2020-08-06 Job assignments The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://medarbetarportalen.gu.se/sahlgrenskaakademin/forskarutbildning/languageId=100001 Project: Bone anchored implants have been introduced in several medical fields for the treatment of a lost musculoskeletal function. However, the underpinning mechanisms of bone formation and long-term remodeling at the bone-implant interface are not fully understood. Novel observations showing Osteocytes, the mechanosensing cells in bone, in direct contact with the implant, indicate that osteocytes are important regulators for bone remodeling and bone maintenance. The interactions between the mechanosensing cells (osteocytes), bone building cells (osteoblasts) and bone resorbing cells (osteoclasts) in relation to the structural development and maintainance of bone-implant interface require detailed studies. The aim of the doctoral project is to elucidate the interplay between mechanical forces, cellular communication and implant properties during bone formation and maintenance. This is a critical aspect in order to understand the concept of osseointegration and, importantly, the underpinning processes of implant failure. The specific research questions addressed during the project are • How do different loads affect signals and communications between osteocytes, osteoblasts and osteoclasts? • How do these events relate to the structure and function of the bone-implant interface with regards to composition and mechanical properties? • How is the healing affected by type 2 diabetes mellitus? The project involves state of the art, cellular and molecular techniques and a broad range of microscopy techniques to evaluate the different hierarchical levels of osseointegration, from nanoscale interactions to macroscale function. Further the project includes in vitro cell culture, experimental in vivo models and studies on patients. The generated knowledge during this project is of fundamental importance for the development of the next generation of implants and treatments for clinical use. Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration (departmental duties). Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post. Eligibility To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements. A person meets the general entry requirements for third-cycle studies if he or she: 1. has been awarded a second-cycle qualification 2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or 3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she: has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies Assessment In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for: - specific knowledge and skills within the subject area and related research fields - experience of scientific theory and relevant research methodology - scientific analysis and presentation verified through thesis, degree project, scientific journals or the like. Employment After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years. Location: Sahlgrenska Academy, Institute of Clinical Sciences, Department of Biomaterials. Extent: 100%. First day of employment: as agreed. Salaries for doctoral students are regulated in a local agreement at the University. For further information regarding the position For more information about the project please contact the principal supervisor, Anders Palmquist, Associate Professor, Institute of Clinical Sciences, e-mail: anders.palmquist@biomaterials.gu.se Unions Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives Information for International Applicants Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: https://www.gu.se/english/welcomeservices/staff https://www.movetogothenburg.com/ How to apply In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. You must include the following, in pdf format Personal letter CV Diploma and transcripts showing that you meet with the general entry requirement Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies If your degree is from a university outside of Sweden, check what you need to submit at https://www.universityadmissions.se/en/All-you-need-to-know1/Applying-for-studies/Documenting-your-eligibility-for-studies/Instructions-for-Masters-applicants/Specific-requirements-for-my-country1/ where you can also see what you need to submit in order to fulfill the English language requirement. If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request. Closing date: 2020-08-06 The University of Gothenburg promotes equal opportunities, equality and diversity. Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned. If you apply for this position please say you saw it on Bioloxy

Doctoral Student in Medical Science - Biomaterial

Diary id:PAR 2020/834

Employment level:Fixed term

Location:Institute of Clinical Sciences

Apply by:2020-08-06

Job assignments

The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://medarbetarportalen.gu.se/sahlgrenskaakademin/forskarutbildning/languageId=100001

Project: Bone anchored implants have been introduced in several medical fields for the treatment of a lost musculoskeletal function. However, the underpinning mechanisms of bone formation and long-term remodeling at the bone-implant interface are not fully understood. Novel observations showing Osteocytes, the mechanosensing cells in bone, in direct contact with the implant, indicate that osteocytes are important regulators for bone remodeling and bone maintenance. The interactions between the mechanosensing cells (osteocytes), bone building cells (osteoblasts) and bone resorbing cells (osteoclasts) in relation to the structural development and maintainance of bone-implant interface require detailed studies. The aim of the doctoral project is to elucidate the interplay between mechanical forces, cellular communication and implant properties during bone formation and maintenance. This is a critical aspect in order to understand the concept of osseointegration and, importantly, the underpinning processes of implant failure.

The specific research questions addressed during the project are

• How do different loads affect signals and communications between osteocytes, osteoblasts and osteoclasts?
• How do these events relate to the structure and function of the bone-implant interface with regards to composition and mechanical properties?
• How is the healing affected by type 2 diabetes mellitus?

The project involves state of the art, cellular and molecular techniques and a broad range of microscopy techniques to evaluate the different hierarchical levels of osseointegration, from nanoscale interactions to macroscale function. Further the project includes in vitro cell culture, experimental in vivo models and studies on patients. The generated knowledge during this project is of fundamental importance for the development of the next generation of implants and treatments for clinical use.

Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration (departmental duties). Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post.

Eligibility

To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studies if he or she:
1. has been awarded a second-cycle qualification
2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or
3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad

A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she: has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

Assessment

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:

- specific knowledge and skills within the subject area and related research fields
- experience of scientific theory and relevant research methodology
- scientific analysis and presentation verified through thesis, degree project, scientific journals or the like.

Employment

After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years.

Location: Sahlgrenska Academy, Institute of Clinical Sciences, Department of Biomaterials. Extent: 100%. First day of employment: as agreed.

Salaries for doctoral students are regulated in a local agreement at the University.

For further information regarding the position

For more information about the project please contact the principal supervisor,
Anders Palmquist, Associate Professor, Institute of Clinical Sciences,
e-mail: anders.palmquist@biomaterials.gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/english/welcomeservices/staff

https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

You must include the following, in pdf format

Personal letter
CV
Diploma and transcripts showing that you meet with the general entry requirement
Proof of completion of English 6 course or the acquired equivalent knowledge through previous studies

If your degree is from a university outside of Sweden, check what you need to submit at https://www.universityadmissions.se/en/All-you-need-to-know1/Applying-for-studies/Documenting-your-eligibility-for-studies/Instructions-for-Masters-applicants/Specific-requirements-for-my-country1/ where you can also see what you need to submit in order to fulfill the English language requirement.

If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

Closing date: 2020-08-06

The University of Gothenburg promotes equal opportunities, equality and diversity.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

If you apply for this position please say you saw it on Bioloxy

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