PhD Fellow in Endocrine Regulation of Metabolism in Drosophila
University of Copenhagen Department of Biology
Denmark

PhD Fellow in Endocrine Regulation of Metabolism in Drosophila

Department of Biology
Faculty of Science

University of Copenhagen

Department of Biology, Faculty of Science at University of Copenhagen is offering a PhD scholarship in investigating the endocrine regulation of metabolism in Drosophila commencing 01.03.2021 or as soon as possible thereafter.

Description of the scientific environment

The Rewitz lab at University of Copenhagen is currently on the lookout for a Ph.D.-student colleague! The lab is working intensively on aspects of endocrine regulation of development, metabolism, and behavior in the fruit fly Drosophila melanogaster, and the projects for which we are recruiting students are in this area.

The Rewitz lab at the moment comprises Prof. Kim Rewitz (Principal Investigator), one Associate Professor, one Assistant Professor, one Ph.D. student, two research assistants, six Master's students, and a laboratory manager/technician. Prior experience with Drosophila genetics and behavior is a strong advantage. No preference will be given in any way to any aspect of the applicant's non-scientific background, including ethnicity, sex and identity, nationality, and so on.

Project description

Endocrine signals from the gut that regulate metabolism

Animal bodies are made up of a collection of different organs, each with different functions. To maintain energy homeostasis, each organ has access to different aspects of information about the internal nutritional state of the animal and of its environment. In our lab, one of our research goals is to identify hormonal signals that regulate metabolism; the gut, as the first organ that can assess recently eaten food, is a likely source of these signals. There are about two thousand potentially secreted proteins encoded in the fly genome, any of which might act as a hormonal signal from the gut to some other tissue – the brain, the fat, or the musculature – apprising them of new nutritional information. In this work, we aim to comprehensively screen the gut "secretome" for metabolism-regulating hormonal signals using tissue-specific gene knockdown and CRISPR manipulations, with phenotypic readouts including metabolite levels, survival, stress resistance, fecundity, and so on. Follow-up studies on identified factors of interest will include, for example, genetic manipulations, metabolomic assessments, and imaging studies to allow us to integrate new signals into known metabolism-regulating frameworks, such as insulin signaling.

Principal supervisor is Professor, Kim Rewitz, Department of Biology, Kim.Rewitz@bio.ku.dk, Direct Phone: +45 6165 6026

Job description

The position is available for a 3-year period and your key tasks as a PhD student at SCIENCE are:

  • To manage and carry through your research project
  • Attend PhD courses
  • Write scientific articles and your PhD thesis
  • Teach and disseminate your research
  • To stay at an external research institution for a few months, preferably abroad
  • Work for the department 

Formal requirements

We are looking for a highly motivated and ambitious scientist with the following qualifications:

  • M.Sc. in Biology, Molecular biosciences, Genetics or other similar fields
  • Experience with genetics and molecular cell biology
  • Experience with invertebrate model organisms; in particular, experience with Drosophila is a plus
  • Expertise in the endocrine regulation of metabolism
  • The ability to communicate in written and spoken English is required
  • The successful applicant will have good communication and interpersonal skills and be well-organized, independent, driven, and curious

Terms of employment

The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

The starting salary is currently at a minimum DKK 331,125 (approx. €43,750) including annual supplement (+ pension at a minimum DKK 53,811). Negotiation for salary supplement is possible.

Application Procedure

The application, in English, must be submitted electronically by clicking APPLY NOW below.

Please include

  • A letter of motivation
  • Curriculum vitae
  • List of publications (if applicable)
  • Copy of relevant diplomas
  • Contact details of 2 persons for references, with associated letters of recommendation
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

The deadline for applications is 17.12.2020, 23:59 GMT +1.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Afterwards an assessment committee will be appointed to evaluate the selected applications. The applicants will be notified of the composition of the committee and the final selection of a successful candidate will be made by the Head of Department, based on the recommendations of the assessment committee and the interview committee.
The main criterion for selection will be the research potential of the applicant and the above mentioned skills. The successful candidate will then be requested to formally apply for enrolment as a PhD student at the PhD school of Science. You can read more about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/.

Questions

For specific information about the PhD scholarship, please contact the principal supervisor [Title, Name, Department of xxx, E-mail, Direct Phone: xxxx].

General information about PhD programmes at SCIENCE is available at https://www.science.ku.dk/phd.

APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Info

Application deadline: 17-12-2020
Employment start: 01-03-2021
Department/Location: Biologisk Institut


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