PhD Fellowship in Chromosome Instability and Human Disease
University of Copenhagen Faculty of Science

PhD Fellowship in ‘Chromosome Instability and Human Disease’ at the Center for Chromosome Stability

A PhD position is available in the Center for Chromosome Stability ( in a group headed by Prof Ian D. Hickson. The post is available from October 1st, 2019 (or at a mutually agreed date). Highly motivated and committed candidates with an interest in chromosome structure and disease are encouraged to apply. 

The post is fully funded, although the post-holder will be encouraged to seek a personal fellowship to support his/her PhD stipend. 

Our group and research 
The CCS is a Center of Excellence funded by the Danish National Research Foundation, and has as its mission on understanding of how chromosomal instability causes human disease. The CCS is embedded at the Department of Cellular and Molecular Medicine ( 

Project description 

The project is part of collaboration between the Hickson and Lopez-Contreras groups in the CCS and will focus on understanding the molecular basis for developmental disorders in man caused by abnormalities in the protein Topoisomerase III (TOP3). TOP3 is required for DNA repair and genome stabilization through altering the topological state of DNA. The project will involve multiple methodologies, including biophysical and cell biological techniques, as well as characterization of a mouse model of the human disease. 

The project will be overseen primarily by Dr. Anna H. Bizard, an expert on DNA topology 

Start:        October 2019.  
Duration: 3 years as a PhD student 

Job description 
  • Your key tasks as a PhD student at SUND are: 
  • Carry through an independent research project under supervision 
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points 
  • Participate in active research environments  
  • Obtain experience with teaching or other types of dissemination related to your PhD project 
  • Write a PhD thesis on the grounds of your project Profile  

We are looking for a highly motivated and enthusiastic person with the following competences and experience:  

  • Must hold a Master’s degree (or equivalent) in a related area of biology or biophysics. 
  • Strong communication and collaboration skills, including the ability to work well in an international academic setting. 

  • Ability to work in a team of multidisciplinary scientists, and the potential to work independently with limited direction. 

  • Excellent written and oral communication skills in English  

  • A track record of publication-standard research 

Key criteria for the assessment of candidates 

Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project e.g. biology, cell biology, biochemistry, molecular biology, biophysics 

Other important criteria are: 
  • Grade point average achieved 
  • Professional qualifications relevant to the PhD programme 
  • Previous publications 
  • Relevant work experience 
  • Other professional activities 
  • Curious mind-set with a strong interest in chromosome biology 
  • Personal drive and commitment to science 
  • Excellent English language skills  
Place of employment 

The place of employment is at Department of Cellular and Molecular Medicine, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories. 
Terms of employment and employment 

The employment as a PhD fellow is full time and for 3 years. Starting date is October 1, 2019 or by agreement. 

The post is conditional upon the candidate’s success­ful enrolment in the PhD school at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the candidate in consultation with the supervisors. 

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the University’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 26.755 DKK /approx. 3.567 EUR (April 2018-level) plus pension. 


For specific information about the PhD scholarship, please contact the principal supervisor. 

General information about PhD programs at the Faculty of Health and Medical Sciences is available at the Graduate School’s website:   

Application procedure 

Your application must be submitted electronically by clicking "Apply". The application must include the following documents in PDF format:   

  1. Motivated letter of application (max. one page)  
  2. CV incl. education, experience, language skills and other skills relevant for the position  
  3. A certified/signed copy of Master of Science certificate. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do  
  4. Publication list (if possible) 

Application deadline:  June 30, 2019, 23.59pm CET  

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. 

The further process  

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.  

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement. 

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.  

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