PhD Position in Parkinson’s Disease Animal Model Development and Validation for Drug Discovery Applications (Catholic University of Leuven)

The laboratory for Neurobiology and gene therapy, headed by Prof. Baekelandt focuses on preclinical Parkinson’s Disease research and has played a pioneering role in recent ground-breaking research, demonstrating a prion-like behaviour of the α-synuclein protein. The group makes use of viral vector technology and molecular imaging as core technologies and is considered a world expert for the application of viral vectors in rodent brain to model and study Parkinson’s disease. Project The Baekelandt lab together with reMYND (www.remynd.com), will submit a Baekeland PhD project (Vlaio) based on the development and validation of Parkinson’s disease models for drug discovery, both in vitro and in vivo. We are currently looking for a motivated PhD student to embark on a 4-year PhD project. The candidate will be involved in the project writing process and is expected to defend the project for the Vlaio review board. The successful candidate will execute and coordinate in vivo experiments in rodents and studies in primary neurons and other cell cultures. Profile Master degree in Medicine, Biomedical Sciences, Bio-engineering, Biology or similar Enthusiastic to work with laboratory animals (rats and mice). Possible techniques include: stereotactic surgery,behavioral analysis, histological and biochemical analyses, primary neuron cultures A curious and creative mind set,eager to learn Proactive and hands-on mindset Perseverant with good problem-solvingskills Ambitious, ability to take ownership of the project and bring the project to a successful end and PhD defense at KU Leuven. Proven proficiency in English,both written and orally Strong writing and analytical skills Good communication and organization skills Ability to meet deadlines Appetite for innovation and transforming research results into industrial applications Capacity to work both as an independent researcher and as part of a team Offer A full-time appointment (100%) as a PhD student for a period of 4 years. You will have to apply for a Baekeland mandate (including evaluation stage) which will be supported by both the laboratory of neurobiology and gene therapy and reMYND. Affiliation to a world-renowned laboratory in Parkinson’s disease and to reMYND (a Leuven-based biotech company focused on development of therapeutics for protein misfolding diseases a world-wide leader of preclinical Alzheimer’s disease CRO), , as part of a motivated interdisciplinary team, with an extensive international network. The possibility to participate and present your research at national and international conferences Training in industrial drugdiscovery through a close collaboration with reMYND Interested? For more information please contact Prof. dr. Veerle Baekelandt, tel.: +32 16 37 40 57, mail: veerle.baekelandt@kuleuven.be or Mrs. Veronique Daniëls, tel.: +32 16 32 63 65, mail: veronique.daniels@kuleuven.be. You can apply for this job no later than July 25, 2020 via the KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be. Employment percentage: Voltijds Location: Leuven Apply before: July 25, 2020 Tags: Neurowetenschappen If you apply for this position please say you saw it on Bioloxy

The laboratory for Neurobiology and gene therapy, headed by Prof. Baekelandt focuses on preclinical Parkinson’s Disease research and has played a pioneering role in recent ground-breaking research, demonstrating a prion-like behaviour of the α-synuclein protein. The group makes use of viral vector technology and molecular imaging as core technologies and is considered a world expert for the application of viral vectors in rodent brain to model and study Parkinson’s disease.

Project

The Baekelandt lab together with reMYND (www.remynd.com), will submit a Baekeland PhD project (Vlaio) based on the development and validation of Parkinson’s disease models for drug discovery, both in vitro and in vivo. We are currently looking for a motivated PhD student to embark on a 4-year PhD project. The candidate will be involved in the project writing process and is expected to defend the project for the Vlaio review board. The successful candidate will execute and coordinate in vivo experiments in rodents and studies in primary neurons and other cell cultures.

Profile

Master degree in Medicine, Biomedical Sciences, Bio-engineering, Biology or similar
Enthusiastic to work with laboratory animals (rats and mice). Possible techniques include: stereotactic surgery,behavioral analysis, histological and biochemical analyses, primary neuron cultures
A curious and creative mind set,eager to learn
Proactive and hands-on mindset
Perseverant with good problem-solvingskills
Ambitious, ability to take ownership of the project and bring the project to a successful end and PhD defense at KU Leuven.
Proven proficiency in English,both written and orally
Strong writing and analytical skills
Good communication and organization skills
Ability to meet deadlines
Appetite for innovation and transforming research results into industrial applications
Capacity to work both as an independent researcher and as part of a team

Offer

A full-time appointment (100%) as a PhD student for a period of 4 years. You will have to apply for a Baekeland mandate (including evaluation stage) which will be supported by both the laboratory of neurobiology and gene therapy and reMYND.
Affiliation to a world-renowned laboratory in Parkinson’s disease and to reMYND (a Leuven-based biotech company focused on development of therapeutics for protein misfolding diseases a world-wide leader of preclinical Alzheimer’s disease CRO), , as part of a motivated interdisciplinary team, with an extensive international network.
The possibility to participate and present your research at national and international conferences
Training in industrial drugdiscovery through a close collaboration with reMYND

Interested?

For more information please contact Prof. dr. Veerle Baekelandt, tel.: +32 16 37 40 57, mail: veerle.baekelandt@kuleuven.be or Mrs. Veronique Daniëls, tel.: +32 16 32 63 65, mail: veronique.daniels@kuleuven.be.

You can apply for this job no later than July 25, 2020 via the

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.

Employment percentage: Voltijds
Location: Leuven
Apply before: July 25, 2020
Tags: Neurowetenschappen

If you apply for this position please say you saw it on Bioloxy

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