PhD Scholarships in Pharmaceutical Sciences
Monash University
Australia

PhD Scholarships - ARC Training Centre for Fragment-Based Design


Job No.: 600590

Location: Parkville campus

Employment type: Full-time

Duration: 3-year fixed-term appointment

Remuneration: ARC scholarship awards provide a stipend of A$32,304 per annum (tax-free)


The Opportunity

We are looking for a highly motivated, passionate and competitive candidate for a fully-funded PhD position in the ARC Training Centre for FragmentBased Design. The successful candidate will join the Centre, directed by Professor Martin Scanlon, which is based at the Monash Institute of Pharmaceutical Sciences (MIPS) at Monash University (Parkville campus).


About the positions

The CFBD is a collaboration between researchers at Monash University, Griffith University, and The University of Sydney. The Centre fosters close partnerships between our university- based researchers and industry-based research end-users to provide transformative research programs and innovative doctoral training in FBD. The strategy of FBD involves screening libraries of small chemical compounds or ‘fragments’ that, owing to their size, generally bind with relatively low affinity and then elaborating these to produce larger, higher affinity ligands (or hits).


This project aims to harness the unique capabilities of the protozoan Tetrahymena to produce recombinant proteins for use in the discovery of novel ligands targeting membrane proteins of importance in human health and biotechnology.


The successful applicant will be working in a multidisciplinary research team in the new ARC Training Centre for Fragment-Based Design (CFBD), where we are working with industry partners to develop new methods for small molecule discovery.


This project is in collaboration with TetraGenetics in Boston and it is a condition of the scholarship that the successful applicant completes a ~12-month placement with the industry partner during and as part of their candidature.


The CFBD is supported by various industry partners including CSIRO, GE Healthcare Australia Pty Ltd, Mestrelab Research SL, Takeda California Inc., TetraGenetics Inc., VAST Bioscience Pty Ltd, Vernalis (R&D) Ltd, BioCurate Pty Ltd, FB Rice Pty Ltd, and Clarivate Analytics Ltd.


Supervisory Team

  • Professor Ray Norton
  • Professor Martin Scanlon


Project Title

Expression and characterisation of membrane proteins in Tetrahymena


The candidates' attributes:

Applications are invited from outstanding and enthusiastic graduates with a relevant background in protein expression and biochemistry.


Students may be domestic or international of high scholarly calibre and will have:

  • A First Class Honours degree, Masters degree or equivalent
  • Analytical thinking, data analysis and critical problem-solving skills
  • Excellent time management skills and ability to work independently
  • An interest in and/or experience working with industry partners
  • Applicants with publications will be highly regarded
  • Fluency in written and oral English


Contact for further information

Informal inquiries are strongly encouraged and should be directed to the Centre Manager,

Dr Narelle Tunstall, Centre Manager, cfbd@monash.edu


Applications

Please email application to Dr Narelle Tunstall, cfbd@monash.edu


Candidates are required to submit the following;

  • CV
  • Transcripts
  • Cover letter

Closing Date

Tuesday 31 March 2020, 11:55 pm AEDT or until filled

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