PhD student – non-coding RNAs in cancer (Ghent University, Department of Biomolecular Medicine)

PhD student – non-coding RNAs in cancer Last application date Mar 31, 2019 23:59 Department GE31 - Department of Biomolecular Medicine Contract Limited duration Degree Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent Occupancy rate 100% Vacancy Type Research staff Job description A position is available for a highly motivated PhD student interested in doing research on circular RNAs in the context of cancer. The candidate will join an international and multidisciplinary team consisting of both bioinformatics and wet-lab experts. The group has a strong research track record on cancer genomics and transcriptomics with a specific interest in the role of non-coding RNAs in cancer as biomarkers or therapeutic targets. Circular RNAs form a fascinating novel class of non-coding RNA, with only a few of them functionally characterized or studied in detail. As circRNAs are stable and abundantly circulating in human blood, they are especially interesting for the discovery of novel cancer biomarkers. The goal of this project is to obtain a set of validated circRNA biomarkers for non-invasive cancer therapy response monitoring and preclinical evidence of novel therapeutic targets. Recently, a large-scale datamining effort in the lab using comprehensive cancer transcriptome data sets has led to the identification of a substantial set of cancer-specific circRNAs. The research of the candidate will consist in the validation and functional characterization of circRNAs from this set. This will involve both wet-lab and bioinformatics experiments/analyses. However, as the candidate will collaborate in a multidisciplinary team, the focus can be tailored based on the interests and skillset of the candidate. The Vandesompele lab is part of the Cancer Research Institute Ghent (CRIG) that unites cancer researchers at Ghent University, Ghent University Hospital and VIB-UGent. Starting date: flexible, as soon as possible Profile of the candidate Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent Highly motivated, eager to learn and team-oriented Excellent oral and written proficiency in English You have a specific interest in and motivation for cancer research Affinity to bioinformatics is recommended How to apply To apply for this position, submit your motivation letter and (scientific) CV to jo.vandesompele@ugent.be. If you apply for this position please say you saw it on Bioloxy

PhD student – non-coding RNAs in cancer

Last application date
Mar 31, 2019 23:59

Department
GE31 - Department of Biomolecular Medicine

Contract
Limited duration

Degree
Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent

Occupancy rate
100%

Vacancy Type
Research staff

Job description

A position is available for a highly motivated PhD student interested in doing research on circular RNAs in the context of cancer. The candidate will join an international and multidisciplinary team consisting of both bioinformatics and wet-lab experts. The group has a strong research track record on cancer genomics and transcriptomics with a specific interest in the role of non-coding RNAs in cancer as biomarkers or therapeutic targets.

Circular RNAs form a fascinating novel class of non-coding RNA, with only a few of them functionally characterized or studied in detail. As circRNAs are stable and abundantly circulating in human blood, they are especially interesting for the discovery of novel cancer biomarkers. The goal of this project is to obtain a set of validated circRNA biomarkers for non-invasive cancer therapy response monitoring and preclinical evidence of novel therapeutic targets.

Recently, a large-scale datamining effort in the lab using comprehensive cancer transcriptome data sets has led to the identification of a substantial set of cancer-specific circRNAs. The research of the candidate will consist in the validation and functional characterization of circRNAs from this set. This will involve both wet-lab and bioinformatics experiments/analyses. However, as the candidate will collaborate in a multidisciplinary team, the focus can be tailored based on the interests and skillset of the candidate.

The Vandesompele lab is part of the Cancer Research Institute Ghent (CRIG) that unites cancer researchers at Ghent University, Ghent University Hospital and VIB-UGent.

Starting date: flexible, as soon as possible

Profile of the candidate

Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent
Highly motivated, eager to learn and team-oriented
Excellent oral and written proficiency in English
You have a specific interest in and motivation for cancer research
Affinity to bioinformatics is recommended