PhD student – non-coding RNAs in cancer Ghent University, Department of Biomolecular Medicine Belgium

PhD student – non-coding RNAs in cancer


Last application date
Mar 31, 2019 23:59


Department
GE31 - Department of Biomolecular Medicine


Contract
Limited duration


Degree
Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent


Occupancy rate
100%


Vacancy Type
Research staff

 

Job description

A position is available for a highly motivated PhD student interested in doing research on circular RNAs in the context of cancer. The candidate will join an international and multidisciplinary team consisting of both bioinformatics and wet-lab experts. The group has a strong research track record on cancer genomics and transcriptomics with a specific interest in the role of non-coding RNAs in cancer as biomarkers or therapeutic targets.

 

Circular RNAs form a fascinating novel class of non-coding RNA, with only a few of them functionally characterized or studied in detail. As circRNAs are stable and abundantly circulating in human blood, they are especially interesting for the discovery of novel cancer biomarkers. The goal of this project is to obtain a set of validated circRNA biomarkers for non-invasive cancer therapy response monitoring and preclinical evidence of novel therapeutic targets.

 

Recently, a large-scale datamining effort in the lab using comprehensive cancer transcriptome data sets has led to the identification of a substantial set of cancer-specific circRNAs. The research of the candidate will consist in the validation and functional characterization of circRNAs from this set. This will involve both wet-lab and bioinformatics experiments/analyses. However, as the candidate will collaborate in a multidisciplinary team, the focus can be tailored based on the interests and skillset of the candidate.

 

The Vandesompele lab is part of the Cancer Research Institute Ghent (CRIG) that unites cancer researchers at Ghent University, Ghent University Hospital and VIB-UGent.

 

Starting date: flexible, as soon as possible

 

Profile of the candidate

  • Master’s degree in (Biomedical) Engineering, Bioinformatics, Pharmaceutical Sciences, (Bio)Medical sciences, or equivalent

  • Highly motivated, eager to learn and team-oriented

  • Excellent oral and written proficiency in English

  • You have a specific interest in and motivation for cancer research

  • Affinity to bioinformatics is recommended

 

How to apply

To apply for this position, submit your motivation letter and (scientific) CV to jo.vandesompele@ugent.be.


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