PhD thesis: Synaptogenesis in the Central Nervous System Ludwig-Maximilians-University Munich, Faculty of Medicine (Biomedical Center) Germany

PhD thesis: Synaptogenesis in the Central Nervous System


Facility: Faculty of Medicine
(Biomedical Center)


Instrumentation Date: from now on


End of the application deadline: 04/30/2019


Salary Scale: 65% TV-L


limitation: for the time being 2 years


There is always the possibility of part-time employment.

 

The Ludwig-Maximilians-Universität München (LMU) is one of the most renowned and largest universities in Germany.

 

tasks
We are looking for a highly-motivated, active and friendly PhD student with interests in cellular and molecular neuroscience to investigate the molecular basis of synaptogenesis in the CNS by analyzing the role of agrim and its receptor complex. This involves the analysis of a transgenic mouse overexpressing TM-agrin in the cortex. For more information see:


Kroger and Pfister (2009) Future Neurology 4: 67 - 86
. Ramseger et al, (2009) J. Biol Chem 284: 7697 to 7705..
Porten et al, (2010) J. Biol.. Chem. 285: 3114-3125.
Karakatsani et al., (2017) Neuronal LRP4 regulates synapse formation in the developing CNS. Development 144, 4604-4615.
Handara et al., (2019) The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Dev Biol 445, 54-67.

 

conditions
Master thesis, excellent communication skills in English (oral and written) and developmental neuroscience are required. Experience in basic research with transgenic animals and confocal microscopy are advantageous.

 

The laboratory is located in the Biomedical Center of the Ludwig Maximilian University in Martinsried. The BMC offers a stimulating environment and state-of-the-art facilities.


We offer you an interesting and responsible job with good training and development opportunities. Handicapped candidates are preferred with otherwise substantially equal suitability. The application of women is welcomed.

 

additional Information
http://www.bmc.med.uni-muenchen.de/index.html

address for applications
Prof. Dr. Stephan Kröger
Biomedical Center
Department of Physiological Genomics
Großhaderner Str. 9
82152 Planegg-Martinsried
E-Mail: skroeger@lmu.de
Contact / in
Prof. Dr. Stephan Kröger


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