Post Doc in Bioinformatics for Epigenomics
Free University of Brussels


Job description:

A postdoctoral position is available for a highly motivated researcher that wishes to join the
Laboratory of Cancer Epigenetics headed by Prof. François Fuks (ULB-Cancer Research Center,
Brussels). The research goal will be the analysis of transcriptomic and epigenomic changes (e.g.
DNA methylation) that arise in cancers. Our major focus is particularly on the analysis of next
generation sequencing data concerning a novel RNA epigenetic modification, which our lab
recently investigated, will be one of the main challenging tasks of the candidate (Lan et al., Nature
Comm., 2020). He/she will participate in several projects with high impact publication potentials.

Working environment:

The candidate will have the possibility to analyse many types of sequencing methods (RNA-seq,
ChIP-seq, RIP-seq, CLIP-seq, Oxford Nanopore, ...), while having a direct interaction with the wet
lab biologists generating the data. The host lab is part of the ULB-Cancer Research Center (U-CRC)
(, providing opportunity to interact with high profile scientific community. The
candidate will join other experienced bioinformaticians working on transcriptomics and
epigenomics. The lab has collaborations in Belgium and abroad, while being international, the
working language is English.


The candidate should hold a PhD (or submitted) in bioinformatics, computational biology,
bioengineering or computer sciences. He/She should demonstrate proficiency in statistics and
programming with R, Python, and/or Bash. Pipeline development and automation will be a plus.
Experience with next-generation sequencing (esp. RNA-seq, ChIP-seq) and clinical data will be
assets. The applicant should have good organizational skills, a taste for interdisciplinary research,
excellent scientific writing and presenting skills and abilty to work independently and with team.
The interaction with the biologists in the lab will be key and genuine interest for biology and
clinical researches is required. This position is funded for 2 years, with the possibility of further
renewal. Screening of applications begins immediately and continues until an outstanding candidate
is selected (flexible starting date).

How to apply?

Informal enquiries, a motivation letter, a CV and names of two referees should be sent to:
Martin BIZET (

Lab website:

Selected publications:

- Lan et al., Nature Comm . 2020
- Bonvin et al., Cancer Res. 2019
- Collignon et al., Science Adv. 2018
- James de Bony E et al, Oncotarget. 2018
- Jeschke*, Bizet* et al., J. Clin. Invest. 2017
- Van Grembergen et al., Science Adv. 2016
- Delatte et al. Science 2016
- Boumahdi et al. Nature 2014
- Deplus et al. Cell Rep. 2014
- Dedeurwaerder*, Defrance* et al.
Briefings in Bioinformatics 2014
- Deplus et al. EMBO J. 2013
- Dedeurwaerder et al. EMBO Mol Med.2011
- Dedeurwaerder*, Defrance* et al.
Epigenomics 2011
- Fuks F. Nature 2010
- Villa et al. Cancer Cell 2007
- Viré et al. Nature 2006

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