Postdoctoral position in Non-Target Analysis Applications with High Resolution Mass Spectrometry (University of Antwerp Faculty of Pharmaceutical, Biomedical and Veterinary Sciences)

Postdoctoral position, Non-Target Analysis Applications with High Resolution Mass Spectrometry Department: Department of Pharmaceutical Sciences – Toxicological Centre (FAR-FFBD) Position status: Full Time Salaried The University and the research group: The University of Antwerp (Flanders, Belgium) is an autonomous and pluralistic institution, supporting a democratic and multicultural society, and is an equal opportunity employer. The University of Antwerp is a young dynamic academic institution for internationally recognized, innovative and pioneering research. Special attention is given to the training of students, and to the innovation of teaching programs. The Toxicological Centre of the Department of Pharmaceutical Sciences is the coordinator of the Centre of Excellence Exposome of the University of Antwerp. It has an extensive experience in human biomonitoring and environmental epidemiology, analytical methods for biomarker analysis, exposure and effect biomarker development, including metabolomics, exposure assessment of emerging contaminants. Applications are invited for a Postdoctoral Research Associate to work under the supervision of Professors Adrian Covaci and Alexander van Nuijs at the Toxicological Centre for a period of up to 24 months, commencing by 1^st September 2020. Your responsibilities Extensive method development and participation in various application projects in the field of i) untargeted and targeted metabolomics; ii) suspect and non-target screening of environmental contaminants in complex matrices (enviromics); iii) structural elucidation of (bio)transformation products of xenobiotics Explore technical capabilities and applying two-dimensional chromatography coupled to ion mobility and high resolution mass spectrometry (quadrupole-time-of-flight QTOF) in a number of research projects Operate, maintain and troubleshoot state of the art instrumentation (Agilent Technologies) Develop and validate LC-HRMS methods to identify endogenous and exogeneous small molecules in biological matrices Participate in the development of analytical and bioinformatics workflows for non-target analysis by HRMS Help organize and (co-)supervise work done on high-resolution mass spectrometry for research and services purposes Help mentor other group members, including undergraduates Coordination, planning, documentation and execution of analyses Promote our work at conferences Contribute to the generation of scientific publications and external funding bids Cooperate with existing and potential customers to plan, execute, discuss and report on small research projects Profile and requirements Hold, or be close to completion of, a PhD in analytical chemistry, mass spectrometry applications in biochemistry, biomedical research, pharmaceutical science or a related area Have experience and good knowledge with the safe handling and use of LC-HRMS and the preparation of biological samples (cells, tissues and bio-fluids) for MS-based metabolomics/enviromics Have experience in bioinformatics to process HRMS data for statistical analyses Have high levels of motivation, good planning, communication and organizational skills Have the ability to manage conflicting demands and meet deadlines Ability to work effectively both independently and in team, both on projects and as part of a multidisciplinary team Possess excellent English communication skills, both written and oral We offer Scientific development opportunities in an international cooperative, interdisciplinary research environment and an excellent working atmosphere in a very dynamic, international and professional team Extensive state-of-the-art equipment and infrastructure The opportunity to present your data on international conferences and participate in workshops A competitive salary according to the University payment scale How to apply? Applications should be sent to adrian.covaci@uantwerpen.be before 1^st June 2020 and must include: your CV a letter of motivation explaining why you are interested in our work and aspire a postdoc the abstract (or a 1-page summary) of your PhD thesis the name and contact details of two references (including promotor of PhD thesis) We will be reviewing candidates until the closing date (or until position is filled). A pre-selection will be made from the submitted applications. The remainder of the selection procedure is specific to the position and will be determined by the selection panel. The University of Antwerp is a family friendly organization, with a focus on equal opportunities and diversity. Our HR-policy for researchers was awarded by the European Commission with the quality label HR Excellence in research. We support the Science4Refugees initiative and encourage asylum-seeking, refugee scientists and researchers to apply for a job at the University of Antwerp. If you apply for this position please say you saw it on Bioloxy

Postdoctoral position, Non-Target Analysis Applications with High Resolution Mass Spectrometry

Department: Department of Pharmaceutical Sciences – Toxicological Centre (FAR-FFBD)

Position status: Full Time Salaried

The University and the research group:

The University of Antwerp (Flanders, Belgium) is an autonomous and pluralistic institution, supporting a democratic and multicultural society, and is an equal opportunity employer. The University of Antwerp is a young dynamic academic institution for internationally recognized, innovative and pioneering research. Special attention is given to the training of students, and to the innovation of teaching programs.

The Toxicological Centre of the Department of Pharmaceutical Sciences is the coordinator of the Centre of Excellence Exposome of the University of Antwerp. It has an extensive experience in human biomonitoring and environmental epidemiology, analytical methods for biomarker analysis, exposure and effect biomarker development, including metabolomics, exposure assessment of emerging contaminants.

Applications are invited for a Postdoctoral Research Associate to work under the supervision of Professors Adrian Covaci and Alexander van Nuijs at the Toxicological Centre for a period of up to 24 months, commencing by 1^st September 2020.

Your responsibilities

Extensive method development and participation in various application projects in the field of i) untargeted and targeted metabolomics; ii) suspect and non-target screening of environmental contaminants in complex matrices (enviromics); iii) structural elucidation of (bio)transformation products of xenobiotics
Explore technical capabilities and applying two-dimensional chromatography coupled to ion mobility and high resolution mass spectrometry (quadrupole-time-of-flight QTOF) in a number of research projects
Operate, maintain and troubleshoot state of the art instrumentation (Agilent Technologies)
Develop and validate LC-HRMS methods to identify endogenous and exogeneous small molecules in biological matrices
Participate in the development of analytical and bioinformatics workflows for non-target analysis by HRMS
Help organize and (co-)supervise work done on high-resolution mass spectrometry for research and services purposes
Help mentor other group members, including undergraduates
Coordination, planning, documentation and execution of analyses
Promote our work at conferences
Contribute to the generation of scientific publications and external funding bids
Cooperate with existing and potential customers to plan, execute, discuss and report on small research projects

Profile and requirements

Hold, or be close to completion of, a PhD in analytical chemistry, mass spectrometry applications in biochemistry, biomedical research, pharmaceutical science or a related area
Have experience and good knowledge with the safe handling and use of LC-HRMS and the preparation of biological samples (cells, tissues and bio-fluids) for MS-based metabolomics/enviromics
Have experience in bioinformatics to process HRMS data for statistical analyses
Have high levels of motivation, good planning, communication and organizational skills
Have the ability to manage conflicting demands and meet deadlines
Ability to work effectively both independently and in team, both on projects and as part of a multidisciplinary team
Possess excellent English communication skills, both written and oral

We offer

Scientific development opportunities in an international cooperative, interdisciplinary research environment and an excellent working atmosphere in a very dynamic, international and professional team
Extensive state-of-the-art equipment and infrastructure
The opportunity to present your data on international conferences and participate in workshops
A competitive salary according to the University payment scale

How to apply?

Applications should be sent to adrian.covaci@uantwerpen.be before 1^st June 2020 and must include:

your CV
a letter of motivation explaining why you are interested in our work and aspire a postdoc
the abstract (or a 1-page summary) of your PhD thesis
the name and contact details of two references (including promotor of PhD thesis)

We will be reviewing candidates until the closing date (or until position is filled). A pre-selection will be made from the submitted applications. The remainder of the selection procedure is specific to the position and will be determined by the selection panel.

The University of Antwerp is a family friendly organization, with a focus on equal opportunities and diversity. Our HR-policy for researchers was awarded by the European Commission with the quality label HR Excellence in research.

We support the Science4Refugees initiative and encourage asylum-seeking, refugee scientists and researchers to apply for a job at the University of Antwerp.

If you apply for this position please say you saw it on Bioloxy

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