Research Associate in Biological Sciences
University of Cambridge
United Kingdom

We are seeking a motivated post-doctoral researcher to develop statistical strategies which support genetic validation of therapeutic targets.


Recent availability of large-scale resources like UK Biobank, with genome-wide genetic data linked to thousands of diseases and related phenotypes now allow Phenome-wide association studies (PheWAS) and related analyses to be performed routinely. These assess the association of specific genetic instruments with a broad range of disease-related phenotypes. The goal of this two year post is to gain expertise in these techniques as they are currently used; to identify opportunities to improve the statistical rigour, and/or power (eg by exploiting additional information) of these methods; and to develop the methods needed to do do.


The post holder will have a PhD in statistics, genetics, bioinformatics or another relevant subject. They will have expertise in high performance computing and data analysis language such as R, Python or Julia.


The post is based within the Wallace group in University of Cambridge (http://chr1swallace.github.io) and funded by GSK and Merck, giving an ideal environment to gain experience of scientific working in academia and industry. The post-holder will be predominantly based within the new Cambridge Institute of Therapeutic Immunology & Infectious Disease (https://www.citiid.cam.ac.uk), and it is envisaged the post-holder will also spend time in both industry locations, and will have regular face-to-face or virtual meetings with both industry partners.


Informal enquiries are welcome, and should be directed to Chris Wallace cew54@cam.ac.uk


Fixed-term: The funds for this post are available for 2 years in the first instance.


Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.


Closing date: 16th February 2020


Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.


Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.


Please quote reference RC22146 on your application and in any correspondence about this vacancy.


The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


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