Research Fellow in Neuroimmunology
University of Southampton, School of Biological Sciences
United Kingdom

Research Fellow in Neuroimmunology

 

Neuroscience

 

Location:  Southampton General Hospital


Salary:   £30,942 to £38,017 per annum 


Full Time - Fixed Term until 28/02/2020


Closing Date:  Wednesday 04 September 2019


Interview Date:   Wednesday 18 September 2019 


Reference:  1172719BJ

 

Applications are invited to join a multidisciplinary team to study the role of the immune system in spreading alpha-synuclein through the brain. Experience in neuroscience, particularly with regard to Parkinson’s disease and inflammation biology is desirable. Candidates will have a PhD* or equivalent professional qualifications and experience in Biological Sciences.

 

Short description of the project: People living with Parkinson’s disease have aggregates of a protein called alpha-synuclein in their brain. As Parkinson’s disease progresses, alpha synuclein spreads through the brain, causing damage to neurons that control movement, balance and speech. Neurons have receptors that can bind to alpha-synuclein fibrils, which help to spread the disease, one of these receptors is called FcγRIIB. In cells isolated from the brain, blocking this receptor prevents the binding and spreading of alpha-synuclein to adjacent neurons.  In this research project, we propose to test if we can block the spread of the neurotoxic alpha synuclein fibrils in a mouse model and if we can develop an antibody therapy that can prevent, or even halt, Parkinson’s disease. 

 

The post is available from 1st October 2019 for a period of 5 months. Interviews are planned for 18th September 2019.

 

Informal enquiries about the post can be made to Professor Jessica Teeling: https://www.southampton.ac.uk/biosci/about/staff/jt8.page

 

The University of Southampton and the School of Biological Sciences both hold an Athena Swan Silver Award, demonstrating their commitment to provide equal opportunities and to advance the representation of women in STEM/M subjects: science, technology, engineering, mathematics and medicine.  Biological Sciences is able to provide flexible working opportunities in a part-time role and due consideration will be given to applicants who have taken a career break.

 

The University has a generous maternity policy and onsite childcare facilities. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.

 

Application Procedure

You should submit your completed application form online at https://jobs.soton.ac.uk.The application deadline will be midnight on the closing date stated above. References are requested along with your application, so please allow time for these to be received prior to the close date, to assist the department with shortlisting. If you need any assistance, please call Geraldine Lewis (Recruitment Team) on +44 (0) 23 8059 3462. Please quote vacancy reference number 1172719BJ on all correspondence.

 

*Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification.  The title of Research Fellow will be applied upon successful completion of the PhD.  Prior to the qualification being awarded the title of Senior Research Assistant will be given.


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