Researcher in Biomedicine
University of Gothenburg Institute of Biomedicine
Sweden

Researcher in Biomedicine

Diary id: PAR 2020/622
Employment level: Fixed term
Location: Institute of Biomedicine
Apply by: 2020-06-05

At present, the institute has about 360 employees and approximately 440 million SEK in total assets.

The Mucin Biology Research Groups at the Sahlgrenska Academy, the Department of Biomedicine, the Department of Medical Biochemistry and Cell Biology are international leaders in the research of mucus (mucus), mucins and its other major components. Mucus is mainly produced by goblet cells and forms in the gut a layer that separates the epithelium from all bacteria. In the respiratory tract, the mucus transports away bacteria, and can form a mucus that protect the epithelium.The research groups currently comprise about 30 researchers with some 30 more in collaborative groups. Responsible is Professor Gunnar C. Hansson and lecturer Malin E. V. Johansson. The groups have very good funding with grants from the European Research Council, Wallenberg Foundation, National Institute of Health USA, the Swedish Research Council, the Swedish Cancer Society and others. For more information, see www.medkem.gu.se/mucinbiology/ The Mucin Biology Research Groups have an international atmosphere where the majority are from countries other than Sweden. All communication is in English.

Job assignments

Central to the project is to isolate and analyze isolated cells with cell sorting (FACS) and confocal microscopy. Expression assays such as RNAseq and Single-cell sequencing in combination with protein expression analysis are very important. The work will also involve mRNA localization (RNA-scope) and immunostaining on whole tissue and sections with confocal microscopy, simpler biochemistry and some molecular biology. You are expected to take responsibility for the project, but also to cooperate within the group, analyze data independently and write for publications. The project aims to study the lung and intestinal mucus protection and mucus secretion from goblet cells. Focus is on understanding how the different types of goblet cells are involved in the protective functions in the lung and gut. The work will be conducted independently around the question of how the various goblet cells contribute to the formation of a dynamic and well-functioning mucus layer on the epithelial surfaces of lung and colon.

Qualifications

The applicant has a doctoral degree and extensive experience of working with epithelial cells, mucin and immunology. Experience in working with animals (mice), FACS, RNAseq, single cell sequencing and confocal microscopy is an absolute requirement. The candidate should also have basic knowledge in cell culture, molecular biology and biochemistry. Of great importance are interpersonal skills and the ability to pursue independent work. To be highly proficient in written and spoken English is a requirement. This position as a researcher intends to constitute a continued employment for junior researchers, and is particularly directed to persons who holds a doctoral degree that is not older than 7 years

Employment

The employment is full-time and limited to 2022-01-31 with placement at the Institute of Biomedicine. First day of employment as agreed.

For further information regarding the position

For further information regarding the position please contact Professor Gunnar C. Hansson. Phone: +46 (0) 31 7863488, +46 (0)709 490 005. E-mail: gunnar.hansson@medkem.gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/english/welcomeservices/staff
https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain proof of completed PhD.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.


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