Researcher in Heart Regeneration in the Zebrafish
University of Bern Institute of Anatomy
Switzerland

Postdoctoral Researcher - Heart regeneration in the zebrafish
80-100%

The group of Nadia Mercader studies the cellular and molecular mechanisms of heart regeneration. Using the zebrafish model and combining genetic manipulations with omic approaches, we investigate how cardiomyocyte proliferation is influenced by different cell types including fibroblasts and macrophages.

We are interested in expanding our team with an expert in bioinformatic analysis (e.g. scRNAseq, ATAQ-Seq, Chip-Seq, WGBS).

Recent publications

Sande-Melón M et al., 2019. Adult sox10+ Cardiomyocytes Contribute to Myocardial Regeneration in the Zebrafish. Cell Rep. doi: 10.1016/j.celrep.2019.09.041

Sanz-Morejón A, García-Redondo AB et al., 2019. Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish. Cell Rep. doi: 10.1016/j.celrep.2019.06.091.

Marques IJ, et al., 2019. Model systems for regeneration: zebrafish. Development. doi: 10.1242/dev.167692.

Andrés-Delgado L, Ernst A, et al., 2019. Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development. doi: 10.1242/dev.174961.

Sánchez-Iranzo H, et al., 2019. Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.1716713115.

Sánchez-Iranzo H, et al.,2019. Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration. Nat Commun. doi: 10.1038/s41467-017-02650-6.

Tasks
  • We are seeking a highly motivated Postdoctoral fellow to work in the field of heart regeneration.
  • The Postdoctoral fellow will be involved in mentoring of Master and PhD students and be invited to contribute to teaching activities.
Requirements
  • A competitive research track record with at least one first author publication in a peer-reviewed journal.
  • Fluent in English including good scientific writing skills, knowledge in German will be a plus.
We offer
    • A postdoctoral position with a competitive salary (for 2 + 1 years; starting date September 2020 or upon agreement).
    • A stimulating, cooperative, and supportive environment and close collaboration with international research teams.
    • The University of Bern is an equal opportunity employer and welcomes all individuals who will contribute to the diversity and excellence of the institution. The University of Bern is committed to support young researchers and offers Initiator Grants and coaching programs among others for postdoctoral fellows.
    • The group is located at the Institute of Anatomy, within the Medical faculty of the University of Bern. It is also embedded into the Cardiovascular research Cluster that includes several groups working at the University of Bern and University Hospital Inselspital.
Please send a curriculum vitae, list of publications, statement of experience, letter of motivation and contact information of 2 references.


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